The Medical Advisor

An evidence‑aware guide to off‑label cancer therapies, integrative oncology, and emerging research — without hype or false promises. This page serves as the central hub for OneDayMD’s coverage of repurposed drugs in cancer care, integrating conventional oncology standards with systems biology, real‑world data, and ethical analysi s. What This Hub Covers (Quick Overview) This hub explains: What repurposed drugs are — and what they are not. Which drugs show credible anti‑cancer signals vs speculation. How repurposed therapies may (or may not) integrate with standard oncology. The evidence hierarchy used across OneDayMD. Safety, ethics, and regulatory realities. It is designed for patients, clinicians, and researchers seeking clarity rather than promotion . Diverse cancer hallmarks targeted by repurposed non-oncology drugs. This figure was created with Biorender.com. Source:  Nature 2024 Executive Summary Repurposed drugs in cancer care refer to existing, FDA‑approved medications o...

A research group from Mexico investigated Ivermectin in Cancer. This is the first study that has tested as many as 28 Cancer types with Ivermectin.  Paper: 2020 (Juarez et al) - Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug.  Ivermectin was tested at 2mg/kg/day which translates to roughly 5uM in vitro concentration. The most sensitive cancer cell lines were: 1. Ovarian 2. Breast 3. Glioblastoma 4. Lung Cancer 5. Colon Cancer 6. Uterine SCC 7. hepatocellular 8. breast TNBC 9. Pancreatic 10. Endometrial. Least sensitive were: 1. osteosarcoma 2. gastric 3. melanoma  Although lymphoma and leukemia cell lines appear to be more resistant to Ivermectin, Ivermectin has a significant impact on those cells' ability to form colonies. So yes, Ivermectin is useful against BOTH lymphomas and leukemias.  Ivermectin also goes after CANCER STEM CELLS, which tend to be resistant to chemotherapy: ...

Facing a cancer diagnosis can feel like navigating an endless maze with no clear direction. The overwhelming emotions and confusion that accompany such news are shared by many. While conventional cancer treatments like chemotherapy and radiation therapy have a role to play, there’s a growing interest in alternative therapies that can complement or even replace traditional methods. Did you know that many  alternative cancer treatments  have been explored, offering new hope to those affected by cancer? Most mainstream cancer treatment guides—including major medical institutions—focus on just listing available 'alternative' cancer therapies (e.g. 'Alternative cancer treatments: 11 options to consider' - by  Mayo Clinic ). Despite the title “Alternative cancer treatments,” the article is  not about cancer cures or alternative oncology systems . It is actually a s upportive care guide (integrative oncology overview disguised as “alternative treatments”). Many patients exp...