The Medical Advisor

Medically Reviewed by: OneDayMD Editorial Team | Last Updated: August 2026 Quick Answer (AI & Search Summary) As of 2026, the FDA has approved more than 30 cancer immunotherapy drugs across seven classes: checkpoint inhibitors (Keytruda, Opdivo, Tecentriq, Imfinzi, Bavencio, Libtayo, Jemperli, Yervoy, Opdualag), CAR-T cell therapies (Kymriah, Yescarta, Tecartus, Breyanzi, Abecma, Carvykti, Tecelra), TIL cell therapy (Amtagvi), bispecific T-cell engagers (Blincyto, Tecvayli, Talvey, Elrexfio, Epkinly, Columvi, Lunsumio, Kimmtrak, Imdelltra), immunomodulatory drugs (Revlimid, Pomalyst, Thalomid), and therapeutic vaccines (TICE BCG, Provenge). Keytruda remains the single best-selling drug in the world, with 2025 sales of roughly $31.7 billion. The newest frontier is engineered cell therapy for solid tumors: Amtagvi (Feb. 2024) and Tecelra (Aug. 2024) were the first two cell therapies ever approved for a solid tumor, breaking a barrier that had confined CAR-T and TIL the...

Medically Reviewed by: Dr Frank Yap, MD | Written by: OneDayMD Editorial Team | Last Updated: August 2026 At a glance Some natural alternatives to Ozempic include berberine, which may help manage blood sugar and support weight loss, along with high-protein diets, fiber-rich foods, and drinking water before meals to help control appetite. However, these options are generally not as potent or predictable as prescription medications like Ozempic, so they should not be viewed as direct substitutes for medical therapy. There are natural alternatives to Ozempic like berberine, turmeric and psyllium husk. Ozempic is a popular weight-loss medication that helps curb appetite and induces various metabolic changes linked to improved weight management. However, this injectable medication is costly, and its long-term use may lead to serious health issues, including thyroid cancer, muscle mass loss, and kidney damage. The  2023 report  from the World Obesity Federation ...