The Medical Advisor

Medically Reviewed by: Dr Frank Yap, MD | Written by: OneDayMD Editorial Team | Last Updated: August 20, 2026 | Part of OneDayMD's Metabolic–Immune Cancer series Quick Answer Systems-level cancer control treats cancer as whole-body biological dysfunction, not just a genetic mutation problem. It targets four modifiable host systems— metabolism, immune function, mitochondrial health, and the tumor microenvironment —that determine whether targeted therapy, chemotherapy, and immunotherapy actually work and keep working. It is an integrative framework that sits alongside standard oncology, not a replacement for it. Table of Contents What Is Systems-Level Cancer Control? Why Targeted Therapy Alone Is Insufficient The Five Pillars of Systems-Level Cancer Control New 2026 Evidence: Insulin Resistance and 12 Cancer Types Seyfried's Metabolic Theory & the Press–Pulse Strategy Dietary Metabolic Strategies Repurposed Drugs Targeting Metabolic & Immune Pathw...

Medically Reviewed by: Dr Frank Yap, MD | Written by:     OneDayMD Editorial Team | Last Updated: July 30, 2026 Dr. William Makis MD (McGill Medicine, 110+ peer-reviewed publications) has treated a large volume of cancer patients using repurposed drugs since 2023 and has documented outcomes publicly on Substack and X. This continuously updated 2026 guide compiles Dr. Makis's latest protocols (from his Substack, X posts through 2026, and direct patient correspondence). We cross-reference his exact dosages, schedules, combinations, safety data, sourcing, and real patient outcomes (anonymized but verifiable on his channels). Important Disclaimer: This content is for educational purposes only and does not constitute medical advice. Ivermectin is used off-label for cancer treatment. Always consult with a knowledgeable physician whom you trust to manage your health. Individual results may vary. Do not self-medicate with ivermectin without proper bloodwork and medical monitoring,...